June 2020: Principal Investigator, Helmholtz Young Investigator,
Max Delbrück Center for Molecular Medicine, Berlin, Germany.
2019-2020: Visiting senior scientist,
Biognosys AG, Schlieren, Switzerland.
2014-2019: Post-Doc, Picotti lab,
ETH Zurich, Switzerland.
PhD, EMBL and University of Heidelberg, Germany.
2009-2014: Pre-Doc, Häring lab,
EMBL Heidelberg, Germany
2008-2009: Research assistant,
University of Cambridge, U.K.
My adventure with my scientific research seriously started with my PhD studies at EMBL in Heidelberg, There I embarked on a project studying the molecular machines regulating chromatin structure and gene expression during the cell cycle using yeast genetics, cell and structural biology. During my PhD I also stumbled into crosslinking mass spectrometry in the Beck laboratory. This brought me to study protein structures with a -omics perspective in the Picotti laboratory at ETH Zurich. There I developed a method that combines limited proteolysis and mass spectrometry to characterise interactions between proteins and metabolites (LiP-SMap, more generally known as LiP-MS). Later, I further optimised LiP-MS to discover protein drug targets on a global scale in collaboration with the proteomics company Biognosys. Now, the goal of my research as group leader is to study how metabolism regulates chromatin architecture and its impact on gene expression using proteomics, genomics and metabolomics.
Outside the lab other kinds of machines and problems bigger than mass spectrometers catch my attention. I read avidly about aviation and space exploration . My element is water, so my favorite sport is swimming.